GALNT10 Antikörper (AA 151-250)

Produktnummer ABIN1714311

Dieser Anti-GALNT10 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von GALNT10 in WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) und ICC. Geeignet für Human.

Kurzübersicht für GALNT10 Antikörper (AA 151-250) (ABIN1714311)

Target: GALNT10 (UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 10 (GalNAc-T10) (GALNT10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GALNT10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Produktdetails anti-GALNT10 Antikörper

Bindungsspezifität: AA 151-250

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GALNT10/GalNAc-T10

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu GALNT10

Target: GALNT10 (UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 10 (GalNAc-T10) (GALNT10))

Andere Bezeichnung: GALNT10/GalNAc-T10

Hintergrund:

Synonyms: DKFZp586H0623, FLJ00205, FLJ11715, GalNAc T10, GalNAc transferase 10, GalNAc-T10, GalNAcT10, GALNT10, GLT10_HUMAN, Polypeptide GalNAc transferase 10, Polypeptide N-acetylgalactosaminyltransferase 10, pp GalNAc T10, pp GaNTase 10, pp-GaNTase 10, ppGalNAcT10, ppGaNTase 10, Protein UDP acetylgalactosaminyltransferase 10, Protein-UDP acetylgalactosaminyltransferase 10, UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 10, UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 10, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10.

Background: The UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes are substrate-specific proteins that catalyze the transfer of GalNAc (N-acetylgalactosaminyl) to serine and threonine residues of various proteins, thereby initiating mucin-type O-linked glycosylation in the Golgi apparatus. GalNAc-T10 (Polypeptide N-acetylgalactosaminyltransferase 10), also known as UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10, is a 603 amino acid single-pass type II membrane protein that prefers Muc5Ac and EA2 peptide substrates. The N-terminal domain is involved in substrate binding and manganese coordination, while the C-terminal domain is involved in UDP-Gal binding and catalytic reaction. GalNAc-T10 is widely expressed, with highest levels found in small intestine. There are four isoforms of GalNAc-T10 that are produced as a result of alternative splicing events.

Gen-ID: 55568